Pharma Labs Esto Suppress and Generation SD Matrix test results

Pharma Labs sell a few bodybuilding products, primarily on the UK supplement market. They’re stocked in gyms, shops and online stores, but the ingredients they list can cause some head-scratching.

Their “Esto Suppress”, sold as a PCT product, lists the active ingredient as “[Z]-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene”.

esto suppress ingredients panelThis is an obscure chemical nomenclature for tamoxifen, the breast cancer drug known by the trade name “Nolvadex” or colloquially as “nolva”. As a medicine, this is illegal to sell without a prescription in the UK under the Medicines Act of 1968. But does Esto Suppress actually contain nolva? Yes, it does. Mostly.
Last week the BMJ (formerly the British Medical Journal) published a letter revealing the results of several sets of tests performed on various samples of Esto Suppress. [1] Three out of four samples showed the presence of tamoxifen, but the amount was highly variable, from 0.9 mg to 3.8 mg per cap. So not only does it contain a prescription-only drug, but it’s also underdosed (the label claims 10mg per cap), and in some cases absent altogether.

sd-matrixGeneration SD Matrix is another product with a lot of question marks over it, not least because the label claims the active ingredient to be “2a,17a-dimethyl-4-androstadiene-3-one,17b-0l”. This ingredient is patently not in the product, as it can’t physically exist. The “SD” part of the name, and the “2a,17a-dimethyl” part of the nomenclature, both seem to indicate that the active ingredient is methasteron (superdrol), but does SD Matrix actually contain superdrol? No, it doesn’t.

SD Matrix test results

The main peak indicates it contains something with a molecular weight around 302.5. This suggests likely candidates to be things like 17a-methyltestosterone, 17a-methyl-1-testosterone (M1T), and 17a-methyl-androsta-1,4-diene-diol (M1,4ADD), which all have a MW of 302.451.
formula weight

The other big peak could be a second unlisted ingredient, an impurity, or an adduct, a product of the testing process.

References:
[1] Evans-Brown, M., Kimergard, A., McVeigh, J., Chandler, M., and Brandt, S.D. (2014). Is the breast cancer drug tamoxifen being sold as a bodybuilding dietary supplement? BMJ 348, g1476–g1476.

© Total Flex Blog 2014